The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 10, 2016
Filed:
Jun. 14, 2013
Applicant:
Sanofi, Paris, FR;
Inventors:
Assignee:
SANOFI, Paris, FR;
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/85 (2006.01); C12P 21/00 (2006.01); C12N 9/00 (2006.01); C07K 16/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/93 (2013.01); C07K 16/00 (2013.01); C12N 15/85 (2013.01); C07K 2317/14 (2013.01); C12N 2800/22 (2013.01); C12N 2820/55 (2013.01); C12N 2830/60 (2013.01); C12Y 603/01002 (2013.01);
Abstract
The present invention is within the field of industrial protein production. The inventors have designed and constructed a new expression system comprising an expression vector coding for a glutamine synthetase of human or dog origin, and a CHO cell line. More specifically, the invention pertains to a combination of (i) a DNA vector suitable for production of a recombinant protein, wherein said vector comprises a sequence coding for a glutamine synthetase, and (ii) a Chinese Hamster Ovary (CHO) cell line, wherein said GS comprises a sequence at least 94.5% identical to the sequence of SEQ ID NO: 1 or to the sequence of SEQ ID NO: 2.