The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 10, 2016

Filed:

Oct. 11, 2012
Applicant:

Snu R&db Foundation, Seoul, KR;

Inventors:

Seong Hoe Park, Seoul, KR;

Kyeong Cheon Jung, Seoul, KR;

Assignee:

SNU R&DB FOUNDATION, Seoul, KR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/28 (2006.01); A61K 45/06 (2006.01); C07K 16/46 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2821 (2013.01); A61K 39/3955 (2013.01); A61K 45/06 (2013.01); C07K 16/46 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/35 (2013.01); C07K 2317/51 (2013.01); C07K 2317/515 (2013.01); C07K 2317/60 (2013.01);
Abstract

Disclosed are a monoclonal antibody targeting domain 2 of ICAM-1 protein and a composition comprising the monoclonal antibody for treating or preventing T cell-mediated immune disease. The antibody of the present application induces antigen-specific T cell tolerance through the regulation of dendritic cell differentiation, and therefore, can be effectively used to treat or prevent autoimmune disease, organ or tissue transplant rejection, and graft-versus-host-disease.


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Park, Seong. (2016). Antibody that binds domain 2 of icam-1 and methods of treatment (U.S. Patent No. 9334326). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9334326

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