The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 10, 2016
Filed:
Mar. 14, 2013
Applicant:
Abbvie Inc., North Chicago, IL (US);
Inventors:
Natarajan Ramasubramanyan, Westborough, MA (US);
Lihua Yang, Westborough, MA (US);
Matthew Omon Herigstad, Charlestown, MA (US);
Hong Yang, Worcester, MA (US);
Christopher Chumsae, North Andover, MA (US);
Assignee:
AbbVie Inc., North Chicago, IL (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); C12P 21/08 (2006.01); A61K 39/395 (2006.01); C07K 16/24 (2006.01); C07K 1/16 (2006.01); C07K 1/18 (2006.01); C12P 21/00 (2006.01); C07K 1/20 (2006.01); C07K 1/22 (2006.01);
U.S. Cl.
CPC ...
C07K 16/241 (2013.01); A61K 39/39591 (2013.01); C07K 1/165 (2013.01); C07K 1/18 (2013.01); C07K 1/20 (2013.01); C07K 1/22 (2013.01); C07K 16/00 (2013.01); C12P 21/00 (2013.01); C07K 2317/14 (2013.01);
Abstract
The instant invention relates to the field of protein production and purification, and in particular to compositions and processes for controlling the amount of charge variants, aggregates, and fragments of a protein of interest, as well as host cell proteins, present in purified preparations by applying particular chromatography conditions during such protein purification.