The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 10, 2016
Filed:
Jun. 25, 2014
Bristol-myers Squibb Company, Princeton, NJ (US);
Douglas G Batt, Wilmington, DE (US);
Myra Beaudoin Bertrand, Lambertville, NJ (US);
George Delucca, Pennington, NJ (US);
Michael A. Galella, Kendall Park, NJ (US);
Soo Sung Ko, Hockessin, DE (US);
Charles M. Langevine, Brooklyn, NY (US);
Qingjie Liu, Newtown, PA (US);
Qing Shi, Princeton, NJ (US);
Anurag S. Srivastava, Belle Mead, NJ (US);
Joseph A. Tino, Lawrenceville, NJ (US);
Scott Hunter Watterson, Pennington, NJ (US);
Bristol-Myers Squibb Company, Princeton, NJ (US);
Abstract
Disclosed are compounds of Formula (I) wherein: the two dotted lines represent either two single or two double bonds; Q is: Ris F, Cl, —CN, or —CH; Ris Cl or —CH; Ris —C(CH)OH or —CHCHOH; Ris H or —CH; each Ris independently F, Cl, —CH, and/or —OCH; and n is zero, 1, or 2. Also disclosed are methods of using such compounds as inhibitors of Bruton's tyrosine kinase (Btk), and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as autoimmune diseases and vascular disease.