The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 10, 2016

Filed:

Apr. 19, 2012
Applicants:

G. K. Surya Prakash, Hacienda Heights, CA (US);

Parag V. Jog, Arcadia, CA (US);

Patrice. T. D Batamack, Culver City, CA (US);

George Olah, Beverly Hills, CA (US);

Inventors:

G. K. Surya Prakash, Hacienda Heights, CA (US);

Parag V. Jog, Arcadia, CA (US);

Patrice. T. D Batamack, Culver City, CA (US);

George Olah, Beverly Hills, CA (US);

Assignee:

University of Southern California, Los Angeles, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 307/44 (2006.01); C07C 29/62 (2006.01); C07C 41/01 (2006.01); C07F 7/08 (2006.01); C07C 29/40 (2006.01); C07C 303/16 (2006.01); C07C 41/30 (2006.01); C07C 41/50 (2006.01); C07C 201/12 (2006.01); C07C 45/45 (2006.01); C07D 213/26 (2006.01); C07D 307/42 (2006.01); C07C 17/269 (2006.01); C07C 17/32 (2006.01); C07B 39/00 (2006.01);
U.S. Cl.
CPC ...
C07D 307/44 (2013.01); C07B 39/00 (2013.01); C07C 17/269 (2013.01); C07C 17/32 (2013.01); C07C 29/40 (2013.01); C07C 29/62 (2013.01); C07C 41/01 (2013.01); C07C 41/30 (2013.01); C07C 41/50 (2013.01); C07C 45/455 (2013.01); C07C 201/12 (2013.01); C07C 303/16 (2013.01); C07D 213/26 (2013.01); C07D 307/42 (2013.01); C07F 7/0818 (2013.01); C07F 7/0896 (2013.01); C07C 2103/24 (2013.01);
Abstract

A direct trifluoromethylation method preferably using a trifluoromethane as a fluoro-methylating species. In particular, the present method is used for preparing a trifluoromethylated substrate by reacting a fluoromethylatable substrate with a trifiuoromethylating agent in the presence of an alkoxide or metal salt of silazane under conditions sufficient to trifluoromethylate the substrate; wherein the fluoromethylatable substrate includes chlorosilanes, carbonyl compounds such as esters, aryl halides, aldehydes, ketones, chalcones, alkyl formates, alkyl halides, aryl halides, alkyl borates, carbon dioxide or sulfur.


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