The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 10, 2016

Filed:

Sep. 20, 2010
Applicants:

Soon Hyeok Hong, Singapore, SG;

Subhash Chandra Ghosh, Singapore, SG;

Yao Zhang, Singapore, SG;

Senthilkumar Muthaiah, Singapore, SG;

Cheng Chen, Singapore, SG;

Xiangya Xu, Singapore, SG;

Inventors:

Soon Hyeok Hong, Singapore, SG;

Subhash Chandra Ghosh, Singapore, SG;

Yao Zhang, Singapore, SG;

Senthilkumar Muthaiah, Singapore, SG;

Cheng Chen, Singapore, SG;

Xiangya Xu, Singapore, SG;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07F 15/00 (2006.01); C07C 231/10 (2006.01); C07D 207/267 (2006.01); C07D 211/76 (2006.01); C07D 223/10 (2006.01); C07D 295/185 (2006.01); C07D 295/192 (2006.01); B01J 31/22 (2006.01);
U.S. Cl.
CPC ...
C07C 231/10 (2013.01); B01J 31/2269 (2013.01); C07D 207/267 (2013.01); C07D 211/76 (2013.01); C07D 223/10 (2013.01); C07D 295/185 (2013.01); C07D 295/192 (2013.01); C07F 15/0046 (2013.01); B01J 2231/763 (2013.01); B01J 2531/821 (2013.01);
Abstract

A process is provided for the synthesis of an amide. A primary or secondary amine and a primary alcohol, with the amine and the alcohol being either moieties of different reactants or moieties of the same molecule, are contacted in the presence of a Ruthenium (II) catalyst. The Ruthenium (II) catalyst is free of a phosphine ligand. The process is also carried out in the absence of a phosphine. Providing the Ruthenium (II) catalyst includes providing an N-heterocyclic carbene.


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