The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 10, 2016

Filed:

Oct. 29, 2009
Applicants:

Scott A. Guelcher, Franklin, TN (US);

Subhabrata Bhattacharyya, Metuchen, NJ (US);

Katarzyna Jadwiga Zienkiewicz, Nashville, TN (US);

Shaun A. Tanner, Charlottesville, VA (US);

Jerald E. Dumas, Nashville, TN (US);

Inventors:

Scott A. Guelcher, Franklin, TN (US);

Subhabrata Bhattacharyya, Metuchen, NJ (US);

Katarzyna Jadwiga Zienkiewicz, Nashville, TN (US);

Shaun A. Tanner, Charlottesville, VA (US);

Jerald E. Dumas, Nashville, TN (US);

Assignees:

Vanderbilt University, Nashville, TN (US);

Warsaw Orthopedic, Inc., Warsaw, IN (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61L 27/44 (2006.01); A61L 27/56 (2006.01);
U.S. Cl.
CPC ...
A61L 27/44 (2013.01); A61L 27/56 (2013.01);
Abstract

Present inventions present composites of bone particles and polyurethane(s), as well as methods of making such composite and uses thereof. A porous composite comprises a plurality of bone particles; and polyurethanes with which the bone particles are combined. To prepare a porous composite, a composition comprise a plurality of bone particles, polyurethane precursors including polyisocyanate prepolymers and polyols, water and catalyst. A composition is either naturally moldable and/or injectable, or it can be made moldable and/or injectable. After implantation or injection, a composition may be set to form a porous composite that provides mechanical strength and supports the in-growth of cells. Inventive composites have the advantage of being able to fill irregularly shape implantation site while at the same time being settable to provide the mechanical strength for most orthopedic applications.


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