The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 10, 2016
Filed:
Dec. 11, 2007
Silvio Aime, Carignano, IT;
Linda Chaabane, Ivrea, IT;
Luciano Lattuada, Bussero, IT;
Vito Lorusso, Bussero, IT;
Edmund R. Marinelli, Lawrenceville, NJ (US);
Pierfrancesco Morosini, Lodi, IT;
Kondareddiar Ramalingam, Dayton, NJ (US);
BO Song, Princeton, NJ (US);
Rolf E. Swenson, Princeton, NJ (US);
Fulvio Uggeri, Codogno, IT;
Silvio Aime, Carignano, IT;
Linda Chaabane, Ivrea, IT;
Luciano Lattuada, Bussero, IT;
Vito Lorusso, Bussero, IT;
Edmund R. Marinelli, Lawrenceville, NJ (US);
Pierfrancesco Morosini, Lodi, IT;
Kondareddiar Ramalingam, Dayton, NJ (US);
Bo Song, Princeton, NJ (US);
Rolf E. Swenson, Princeton, NJ (US);
Fulvio Uggeri, Codogno, IT;
Bracco Imaging SpA, Milan, IT;
Abstract
The present invention relates to a novel class of diagnostically or therapeutically effective compounds comprising novel peptides able to bind fibrin, to a process for their preparation and to compositions thereof for use in therapy and diagnostics. The compounds of the invention bind, in particular, to fibrin present in the extracellular matrix (EC) of tumor or connective tissue of stroma thus acting as targeting moieties able to bring and successfully bound an active moiety linked thereto to fibrin depositions inside solid tumors.