The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 10, 2016
Filed:
Jul. 20, 2011
Marina Caldarelli, Milan, IT;
Italo Beria, Nerviano, IT;
Nicoletta Colombo, Bergamo, IT;
Claudia Piutti, Nerviano, IT;
Matteo Salsa, Bellinzago Novarese, IT;
Gabriella Traquandi, Milan, IT;
Marina Caldarelli, Milan, IT;
Italo Beria, Nerviano, IT;
Nicoletta Colombo, Bergamo, IT;
Claudia Piutti, Nerviano, IT;
Matteo Salsa, Bellinzago Novarese, IT;
Gabriella Traquandi, Milan, IT;
NERVIANO MEDICAL SCIENCES S.R.L., Nerviano (MI), IT;
Abstract
The present invention relates to substituted isoxazolo-quinazolines which modulate the activity of protein kinases and are therefore useful in treating diseases caused by dysregulated protein kinase activity, in particular human MPS1 and PERK. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing such these compounds or the pharmaceutical compositions containing them.