The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 03, 2016
Filed:
Oct. 18, 2013
Applicant:
Kaohsiung Medical University, Kaohsiung, TW;
Inventors:
Tian-Lu Cheng, Kaohsiung, TW;
Steven R. Roffler, Kaohsiung, TW;
Kuo-Hsiang Chuang, Kaohsiung, TW;
Ssu-Jung Lu, Kaohsiung, TW;
Assignee:
KAOHSIUNG MEDICAL UNIVERSITY, Kaohsiung, TW;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); G01N 33/554 (2006.01); G01N 33/68 (2006.01); G01N 33/94 (2006.01); C07K 16/44 (2006.01);
U.S. Cl.
CPC ...
G01N 33/554 (2013.01); C07K 16/44 (2013.01); G01N 33/5308 (2013.01); G01N 33/6857 (2013.01); G01N 33/94 (2013.01); G01N 33/9493 (2013.01); C07K 2317/56 (2013.01); C07K 2319/03 (2013.01); C12N 2503/02 (2013.01); C12N 2510/04 (2013.01); G01N 2430/60 (2013.01); G01N 2440/28 (2013.01);
Abstract
The present invention provides a method for preparing an isolated eukaryotic cell which presents an anti-polyethylene glycol (PEG) antibody on a cell membrane. The present invention also provides a method for a quantitative analysis of a polyethylene glycol (PEG) by said anti-PEG antibody expressing cell. The cell-based quantitative analysis of the present prevention could sensitively quantify free PEG and PEG-modified macromolecules (proteins, nanoparticles and liposomes) as sensitive as nano-gram level.