The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 03, 2016
Filed:
Oct. 06, 2011
Applicants:
Stephen R. Quake, Stanford, CA (US);
Sebastian J. Maerkl, Palo Alto, CA (US);
Inventors:
Stephen R. Quake, Stanford, CA (US);
Sebastian J. Maerkl, Palo Alto, CA (US);
Assignee:
California Institute of Technology, Pasadena, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/563 (2006.01); G01N 33/543 (2006.01); G01N 33/53 (2006.01); B01L 3/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/54393 (2013.01); B01L 3/502707 (2013.01); B01L 3/502738 (2013.01); G01N 33/5302 (2013.01); B01J 2219/0043 (2013.01); B01L 3/5027 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0819 (2013.01); B01L 2300/0861 (2013.01); B01L 2300/123 (2013.01); B01L 2400/0481 (2013.01); B01L 2400/0655 (2013.01);
Abstract
The invention provides devices and methods for surface patterning the substrate of a microfluidic device, and for detection and analysis of interactions between molecules by mechanically trapping a molecular complex while substantially expelling solvent and unbound solute molecules. Examples of molecular complexes include protein-protein complexes and protein-nucleic acid complexes.