The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 03, 2016

Filed:

Jan. 20, 2010
Applicants:

Michael F. Clarke, Palo Alto, CA (US);

Stephen R. Quake, Stanford, CA (US);

Piero D. Dalerba, Palo Alto, CA (US);

Huiping Liu, Chicago, IL (US);

Anne Leyrat, San Carlos, CA (US);

Tomer Kalisky, Palo Alto, CA (US);

Maximilian Diehn, Stanford, CA (US);

Jianbin Wang, Stanford, CA (US);

Inventors:

Michael F. Clarke, Palo Alto, CA (US);

Stephen R. Quake, Stanford, CA (US);

Piero D. Dalerba, Palo Alto, CA (US);

Huiping Liu, Chicago, IL (US);

Anne Leyrat, San Carlos, CA (US);

Tomer Kalisky, Palo Alto, CA (US);

Maximilian Diehn, Stanford, CA (US);

Jianbin Wang, Stanford, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5023 (2013.01); C12Q 1/6886 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/112 (2013.01); C12Q 2600/136 (2013.01); C12Q 2600/178 (2013.01); G01N 2800/52 (2013.01);
Abstract

Methods are provided for diagnosis and prognosis of disease by analyzing expression of a set of genes obtained from single cell analysis. Classification allows optimization of treatment, and determination of whether on whether to proceed with a specific therapy, and how to optimize dose, choice of treatment, and the like. Single cell analysis also provides for the identification and development of therapies which target mutations and/or pathways in disease-state cells.


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