The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 03, 2016

Filed:

May. 09, 2014
Applicants:

Muhammed Majeed, Edison, NJ (US);

Kalyanam Nagabhushanam, East Windsor, NJ (US);

Anju Majeed, Piscataway, NJ (US);

Bani Sarang, Bangalore, IN;

Anjali Pandey, Bangalore, IN;

Inventors:

Muhammed Majeed, Edison, NJ (US);

Kalyanam Nagabhushanam, East Windsor, NJ (US);

Anju Majeed, Piscataway, NJ (US);

Bani Sarang, Bangalore, IN;

Anjali Pandey, Bangalore, IN;

Assignee:

SAMI LABS LIMITED, Bangalore, IN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/235 (2006.01); A61K 31/215 (2006.01); C12N 5/077 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0653 (2013.01); A61K 31/235 (2013.01); C12N 2500/76 (2013.01);
Abstract

The present invention discloses the potential of Calebin A in inhibiting adipogenesis and applications thereof in obesity management. The present invention elucidates the potential of Calebin A to favorably modulate biochemical markers associated with obesity. Notable biomodulatory properties of Calebin A include inhibiting leptin production, increasing adiponectin expression and inhibiting local (adipocyte) and systemic inflammation caused by pro-inflammatory cytokines Tumor Necrosis Factor (TNF-α), Interleukin-6 (IL-6) and Interleukin-1 (IL-1β).


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