The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 03, 2016
Filed:
Dec. 17, 2014
Applicant:
Eli Lilly and Company, Indianapolis, IN (US);
Inventors:
Hector Aldaz, San Marcos, CA (US);
Barrett Allan, Encinitas, CA (US);
Ling Liu, Carmel, IN (US);
Jirong Lu, Carmel, IN (US);
Ying Tang, San Diego, CA (US);
Sheng-Hung Rainbow Tschang, Carmel, IN (US);
Pia Pauliina Yachi, San Diego, CA (US);
Assignee:
Eli Lilly and Company, Indianapolis, IN (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/40 (2006.01); C07K 16/28 (2006.01); C07K 16/30 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/40 (2013.01); C07K 16/2863 (2013.01); C07K 16/30 (2013.01); C07K 16/3023 (2013.01); C07K 16/3046 (2013.01); A61K 2039/505 (2013.01); C07K 2317/31 (2013.01); C07K 2317/60 (2013.01); C07K 2317/622 (2013.01); C07K 2317/73 (2013.01); C07K 2317/77 (2013.01); C07K 2317/92 (2013.01);
Abstract
Provided are multifunctional antibodies, and/or antigen-binding fragments, that bind to, and inhibit the activity of, both human epidermal growth factor receptor (EGFR) and MET, and that are effective in treating cancers and other diseases, disorders, or conditions where pathogenesis is mediated by EGFR and MET.