The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 03, 2016
Filed:
Jan. 07, 2005
Nicholas Pullen, Sandwich, GB;
Elizabeth Molloy, Sandwich, GB;
Sirid-aimée Kellermann, Menlo Park, CA (US);
Larry L. Green, San Francisco, CA (US);
Mary Haak-frendscho, Newark, CA (US);
Nicholas Pullen, Sandwich, GB;
Elizabeth Molloy, Sandwich, GB;
Sirid-Aimée Kellermann, Menlo Park, CA (US);
Larry L. Green, San Francisco, CA (US);
Mary Haak-Frendscho, Newark, CA (US);
Pfizer Inc., New York, NY (US);
Amgen Fremont Inc., Fremont, CA (US);
Abstract
The present invention relates to antibodies, including human antibodies, and antigen-binding portions thereof that specifically bind to MAdCAM, preferably human MAdCAM, and inhibit MAdCAM. The antibodies comprise the CDRs or variable domains derived from an antibody produced by the hybridoma cell line 7.16.6 (ECACC Accession No. 03090909) or from an antibody comprising the amino acid sequences of SEQ ID NOs.: 34 and 36. The invention also relates to nucleic acid molecules encoding such antibodies and antigen-binding portions thereof, methods of making and using the antibodies and portions, and compositions comprising these antibodies and portions.