The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 03, 2016
Filed:
Aug. 02, 2011
Robert Horlick, San Diego, CA (US);
David King, Encinitas, CA (US);
Peter Bowers, San Diego, CA (US);
Jennifer Dalton, Cardiff, CA (US);
Betty Wu, San Diego, CA (US);
Traci Roberts, San Diego, CA (US);
Xue Zhang, San Diego, CA (US);
Laurence Altobell, Iii, San Diego, CA (US);
Robert Horlick, San Diego, CA (US);
David King, Encinitas, CA (US);
Peter Bowers, San Diego, CA (US);
Jennifer Dalton, Cardiff, CA (US);
Betty Wu, San Diego, CA (US);
Traci Roberts, San Diego, CA (US);
Xue Zhang, San Diego, CA (US);
Laurence Altobell, III, San Diego, CA (US);
AnaptysBio, Inc., San Diego, CA (US);
Abstract
The invention relates to an isolated interleukin-17 (IL-17)-binding agent which comprises an immunoglobulin heavy chain polypeptide comprising SEQ ID NO: 1, SEQ ID NO: 32, SEQ ID NO: 33, SEQ ID NO: 78, or SEQ ID NO: 79, and an immunoglobulin light chain polypeptide comprising SEQ ID NO: 23, except that one or more specific of residues of SEQ ID NO: 1 and SEQ ID NO: 23 are replaced with a different residue. The invention also provides vectors, compositions, and methods of using the IL-17-binding agent to treat an IL-17-mediated disease.