The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 03, 2016
Filed:
Oct. 28, 2011
Keisuke Ishii, Tokyo, JP;
Keiko Katsumi, Chiba, JP;
Tadashi Matsuura, Ibaraki, JP;
Yukio Sudo, Tokyo, JP;
Katsuyuki Mitomo, Tokyo, JP;
Katsushi Kouda, Tokyo, JP;
Keisuke Ishii, Tokyo, JP;
Keiko Katsumi, Chiba, JP;
Tadashi Matsuura, Ibaraki, JP;
Yukio Sudo, Tokyo, JP;
Katsuyuki Mitomo, Tokyo, JP;
Katsushi Kouda, Tokyo, JP;
PERSEUS PROTEOMICS INC., Tokyo, JP;
Abstract
It is an object of the present invention to provide an anti-cadherin antibody having a high internalization capacity and provide an anti-cadherin antibody-drug conjugate that effectively kills cadherin-expressing cancer cells with the use of such antibody. The present invention provides an anti-cadherin antibody which recognizes a cadherin domain 1 (EC1) of cadherin and exhibits a high internalization capacity.