The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 03, 2016
Filed:
Apr. 17, 2013
Astellas Pharma Inc., Chuo-ku, JP;
Yutaka Nakajima, Tokyo, JP;
Sunao Imada, Tokyo, JP;
Yuji Takasuna, Tokyo, JP;
Naohiro Aoyama, Tokyo, JP;
Takahiro Nigawara, Tokyo, JP;
Shohei Shirakami, Tokyo, JP;
Fumiyuki Shirai, Tokyo, JP;
Junji Sato, Tokyo, JP;
Keita Nakanishi, Tokyo, JP;
Kaori Kubo, Tokyo, JP;
Astellas Pharma Inc., Chuo-ku, JP;
Abstract
[Problem] On the basis of a cathepsin S inhibitory effect, an excellent agent for treating or preventing autoimmune disease, allergic disease, graft rejection of an organ, bone marrow or tissue, systemic lupus erythematosus, or the like is provided. [Means for Solution] It was found that a nitrogen-containing bicyclic heterocyclic compound has the excellent cathepsin S inhibitory effect, thereby completing the invention. The compound of the present invention has the cathepsin S inhibitory effect, and can be used as an agent for preventing and/or treating autoimmune disease, allergic disease, graft rejection of an organ, bone marrow or tissue, systemic lupus erythematosus, or the like.