The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 03, 2016

Filed:

Dec. 31, 2011
Applicants:

Changyou Zhou, Princeton, NJ (US);

BO Ren, Beijing, CN;

Hexiang Wang, Beijing, CN;

Inventors:

Changyou Zhou, Princeton, NJ (US);

Bo Ren, Beijing, CN;

Hexiang Wang, Beijing, CN;

Assignee:

BeiGene Ltd., Grand Cayman, KY;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/5025 (2006.01); C07D 237/26 (2006.01); C07D 471/14 (2006.01); C07D 471/06 (2006.01); C07D 471/16 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 471/14 (2013.01); C07D 471/04 (2013.01); C07D 471/06 (2013.01); C07D 471/16 (2013.01);
Abstract

The present invention provides a compound of Formula (I): wherein the variables Z, n, Y and p are as defined herein, and pharmaceutically acceptable salts thereof, which can inhibit the activity of poly (ADP-ribose)polymerases, and pharmaceutical compositions comprising the same.


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