The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 03, 2016

Filed:

Oct. 17, 2014
Applicant:

Adhaere Pharmaceuticals, Inc., Miami, FL (US);

Inventor:

Vineet Gupta, Pinecrest, FL (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61N 5/10 (2006.01); A61K 31/337 (2006.01); A61K 31/427 (2006.01); C07D 417/06 (2006.01); A61K 45/06 (2006.01); A61K 31/5377 (2006.01); C07D 417/14 (2006.01);
U.S. Cl.
CPC ...
C07D 417/06 (2013.01); A61K 31/337 (2013.01); A61K 31/427 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01); A61N 5/10 (2013.01); C07D 417/14 (2013.01);
Abstract

A method of treating inflammation, by administering an effective amount of a β2 integrin agonist to a patient, and reducing inflammation. A method of treating cancer, by administering an effective amount of a β2 integrin agonist to a patient, and reducing tumor growth. A method of treating a patient exposed to radiation, by administering an effective amount of a β2 integrin agonist to the patient after radiation exposure, and mitigating the effects of radiation exposure in the patient. A method of preventing effects of radiation, by administering an effective amount of a β2 integrin agonist to the patient prior to radiation exposure, and preventing the effects of radiation exposure on the patient. A method of treating acquired bone marrow failure (BMF), by administering an effective amount of a β2 integrin agonist to a patient. Methods of improving the health of damaged vasculature in a patient and activating β2 integrins.


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