The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 03, 2016

Filed:

Oct. 24, 2014
Applicants:

Array Biopharma Inc., Boulder, CO (US);

Genentech, Inc., South San Francisco, CA (US);

Inventors:

Anna Leivers, Boulder, CO (US);

Josef R. Bencsik, Boulder, CO (US);

James F. Blake, Boulder, CO (US);

Martin F. Hentemann, Boulder, CO (US);

Nicholas C. Kallan, Boulder, CO (US);

Jun Liang, South San Francisco, CA (US);

Ian S. Mitchell, Boulder, CO (US);

Stephen T. Schlachter, Boulder, CO (US);

Eli M. Wallace, Boulder, CO (US);

Rui Xu, Boulder, CO (US);

Tony P. Tang, Boulder, CO (US);

Assignees:

GENENTECH, INC., South San Francisco, CA (US);

ARRAY BIOPHARMA INC., Boulder, CO (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 239/70 (2006.01); C07D 401/10 (2006.01); C07D 401/04 (2006.01); C07D 409/04 (2006.01); C07D 417/04 (2006.01); C07D 487/04 (2006.01); C07D 401/12 (2006.01); C07D 403/04 (2006.01); C07D 403/10 (2006.01); C07D 417/10 (2006.01); C07D 211/08 (2006.01); C07D 211/46 (2006.01);
U.S. Cl.
CPC ...
C07D 401/10 (2013.01); C07D 211/08 (2013.01); C07D 211/46 (2013.01); C07D 239/70 (2013.01); C07D 401/04 (2013.01); C07D 401/12 (2013.01); C07D 403/04 (2013.01); C07D 403/10 (2013.01); C07D 409/04 (2013.01); C07D 417/04 (2013.01); C07D 417/10 (2013.01); C07D 487/04 (2013.01);
Abstract

Compounds of Formula I are useful for inhibiting AKT protein kinases. Methods of using compounds of Formula I and stereoisomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.


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