The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 03, 2016

Filed:

Nov. 30, 2012
Applicant:

Hangzhou Bensheng Pharmaceutical Co., Ltd., Zhejiang, CN;

Inventors:

Rongzhen Xu, Zhejiang, CN;

Frank Rong, Zhejiang, CN;

Fuwen Xie, Fujian, CN;

Hongxi Lai, Fujian, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 307/77 (2006.01); C07D 405/12 (2006.01);
U.S. Cl.
CPC ...
C07D 307/77 (2013.01); C07D 405/12 (2013.01);
Abstract

The present invention belongs to the field of natural medicine and pharmaceutical chemistry, and specifically relates to novel 2-aminated methylene or 2-esterified methylene tanshinone I derivatives of formula (I) or a pharmaceutically acceptable salt thereof, to a process for the preparation of these compounds, compositions containing such compounds and their use in preparing antineoplastic medicaments. When X is nitrogen, formula I indicates 2-aminated methylene tanshinone I; when X is oxygen, formula I indicates 2-esterified methylene tanshinone I.


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