The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 03, 2016
Filed:
Dec. 03, 2008
Applicants:
Marcello Allegretti, L'Aquila, IT;
Riccardo Bertini, L'Aquila, IT;
Maria Candida Cesta, L'Aquila, IT;
Cinzia Bizzarri, L'Aquila, IT;
Francesco Colotta, L'Aquila, IT;
Inventors:
Marcello Allegretti, L'Aquila, IT;
Riccardo Bertini, L'Aquila, IT;
Maria Candida Cesta, L'Aquila, IT;
Cinzia Bizzarri, L'Aquila, IT;
Francesco Colotta, L'Aquila, IT;
Assignee:
DOMPE' FARMACEUTICI S.P.A., Milan, IT;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 317/24 (2006.01); C07C 311/21 (2006.01); C07C 309/65 (2006.01); C07C 271/18 (2006.01); C07C 69/738 (2006.01); C07C 49/782 (2006.01); C07C 49/215 (2006.01); C07C 49/213 (2006.01); C07D 319/06 (2006.01); C07D 213/50 (2006.01); C07D 209/46 (2006.01); A61K 31/12 (2006.01); A61K 31/192 (2006.01); A61K 31/662 (2006.01); A61K 31/10 (2006.01); A61K 31/44 (2006.01); A61P 29/00 (2006.01); C07C 45/56 (2006.01); C07C 45/67 (2006.01); C07F 9/40 (2006.01);
U.S. Cl.
CPC ...
C07C 69/738 (2013.01); C07C 45/562 (2013.01); C07C 45/673 (2013.01); C07C 45/676 (2013.01); C07C 49/213 (2013.01); C07C 49/215 (2013.01); C07C 49/782 (2013.01); C07C 271/18 (2013.01); C07C 309/65 (2013.01); C07C 311/21 (2013.01); C07C 317/24 (2013.01); C07D 209/46 (2013.01); C07D 213/50 (2013.01); C07D 319/06 (2013.01); C07F 9/4059 (2013.01); C07B 2200/07 (2013.01);
Abstract
The compounds of formula (I): where Ar is an aromatic ring and Ra, Rb, are as defined in the description, are useful in therapy as drugs for the treatment of diseases mediated by infiltrations of neutrophils induced by IL-8, such as psoriasis, rheumatoid arthritis, ulcerative cholitis and for the treatment of damages caused by ischemia and reperfusion.