The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 03, 2016
Filed:
Jan. 17, 2014
Applicant:
United Therapeutics Corporation, Silver Spring, MD (US);
Inventors:
Roger Andrew Jeffs, Chapel Hill, NC (US);
David Zaccardelli, Cary, NC (US);
Assignee:
United Therapeutics Corporation, Silve Spring, MD (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/198 (2006.01); A61K 31/5575 (2006.01); A61K 47/18 (2006.01); A61K 9/00 (2006.01); A61K 47/02 (2006.01);
U.S. Cl.
CPC ...
A61K 47/18 (2013.01); A61K 9/0019 (2013.01); A61K 31/5575 (2013.01); A61K 47/183 (2013.01); A61K 47/02 (2013.01);
Abstract
Buffer solutions for pharmaceutical preparations that have bactericidal activity preferentially against gram negative bacteria are provided. The buffers have a pH of greater than about 10 or less than about 4.5 with low buffer capacity. Methods of their use in reducing the occurrence of blood stream infections in a mammal is also provided.