The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 03, 2016
Filed:
Jul. 02, 2014
Applicant:
Genentech, Inc., South San Francisco, CA (US);
Inventors:
James John Crawford, San Francisco, CA (US);
Wendy Lee, San Ramon, CA (US);
Wendy B. Young, San Mateo, CA (US);
Assignee:
Genentech, Inc., South San Francisco, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61P 11/06 (2006.01); A61K 31/519 (2006.01); A61K 45/06 (2006.01); C07D 401/14 (2006.01); A61K 31/4985 (2006.01); A61K 31/502 (2006.01); A61K 31/5025 (2006.01); C07D 401/10 (2006.01); C07D 471/04 (2006.01); C07D 471/14 (2006.01); C07D 487/04 (2006.01); C07D 495/04 (2006.01); A61K 31/444 (2006.01); A61K 31/4725 (2006.01);
U.S. Cl.
CPC ...
A61K 31/519 (2013.01); A61K 31/444 (2013.01); A61K 31/4725 (2013.01); A61K 31/4985 (2013.01); A61K 31/502 (2013.01); A61K 31/5025 (2013.01); A61K 45/06 (2013.01); C07D 401/10 (2013.01); C07D 401/14 (2013.01); C07D 471/04 (2013.01); C07D 471/14 (2013.01); C07D 487/04 (2013.01); C07D 495/04 (2013.01);
Abstract
Heteroaryl pyridone and aza-pyridone amide compounds of Formula I are provided, and various substituents including stereoisomers, tautomers, and pharmaceutically acceptable salts thereof, useful for inhibiting Btk, and for treating cancer and immune disorders such as inflammation mediated by Btk. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, and treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.