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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9326951 B1

PDFFull Text
Date of Patent:
May. 03, 2016

Filed:

Jun. 20, 2012

Cell-free tissue engineered vascular grafts

Applicants:

Christopher K. Breuer, New Albany, OH (US);

Tarek Fahmy, New Haven, CT (US);

Inventors:

Christopher K. Breuer, New Albany, OH (US);

Tarek Fahmy, New Haven, CT (US);

Assignee:

Yale University, New Haven, CT (US);

Attorney:

Pabst Patent Group LLP

Primary Examiner:

Robert A Wax

Assistant Examiner:

Tracy Liu

Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61P 35/00 (2006.01); A61K 9/70 (2006.01); A61L 27/50 (2006.01); A61L 27/54 (2006.01); A61L 27/58 (2006.01); A61K 31/663 (2006.01);
U.S. Cl.
CPC ...
A61K 9/7023 (2013.01); A61K 31/663 (2013.01); A61L 27/507 (2013.01); A61L 27/54 (2013.01); A61L 27/58 (2013.01); A61L 2300/602 (2013.01); A61L 2300/62 (2013.01); A61L 2300/622 (2013.01); A61L 2300/624 (2013.01);
Abstract

A composition containing a macrophage inhibitor may be administered in an effective amount to prevent, inhibit or reduce restenosis, thrombus or aneurysm formation in implanted polymeric vascular grafts. The composition may be administered prior to vascular graft implantation, at the same time as vascular graft implantation, following vascular graft implantation, or any combination thereof. Exemplary macrophage inhibitors include bisphosphonates, anti-folate drugs and antibodies, preferably in a controlled release or liposomal formulation.

Find Patent Forward Citations

Breuer, Christopher. (2016). Cell-free tissue engineered vascular grafts (U.S. Patent No. 9326951). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9326951

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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