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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9326948 B1

PDFFull Text
Date of Patent:
May. 03, 2016

Filed:

Nov. 08, 2011

Implants for 'load bearing' bone substitutions having hierarchical organized architecture deriving from transformation of vegetal structures

Applicants:

Anna Tampieri, Faenza, IT;

Simone Sprio, Bologna, IT;

Andrea Ruffini, Bagnacavallo, IT;

Julia Will, Obermichelbach, DE;

Peter Greil, Weisendorf, DE;

Frank Muller, Jena, DE;

Julian Martinez Fernandez, Seville, ES;

Carmen Torres Raya, Mairena del Aljarafe, ES;

Francisco Manuel Varela Feria, Seville, ES;

Joaquin Ramirez Rico, Tomares, ES;

Marie-francoise Harmand, Bordeaux, FR;

Inventors:

Anna Tampieri, Faenza, IT;

Simone Sprio, Bologna, IT;

Andrea Ruffini, Bagnacavallo, IT;

Julia Will, Obermichelbach, DE;

Peter Greil, Weisendorf, DE;

Frank Muller, Jena, DE;

Julian Martinez Fernandez, Seville, ES;

Carmen Torres Raya, Mairena del Aljarafe, ES;

Francisco Manuel Varela Feria, Seville, ES;

Joaquin Ramirez Rico, Tomares, ES;

Marie-Francoise Harmand, Bordeaux, FR;

Assignee:

CONSIGLIO NAZIONALE DELLE RICERCHE, Rome, IT;

Attorney:

Pearne & Gordon LLP

Primary Examiner:

Ernst V Arnold

Int. Cl.
CPC ...
A61F 2/28 (2006.01); A61K 38/39 (2006.01); A61L 27/10 (2006.01); A61L 27/12 (2006.01); A61L 27/46 (2006.01); A61K 9/50 (2006.01); A61L 27/56 (2006.01);
U.S. Cl.
CPC ...
A61K 9/501 (2013.01); A61F 2/28 (2013.01); A61K 38/39 (2013.01); A61L 27/10 (2013.01); A61L 27/12 (2013.01); A61L 27/46 (2013.01); A61L 27/56 (2013.01); A61L 2430/02 (2013.01);
Abstract

The present invention relates to a bone substitute comprising a core based on hydroxyapatite (HA), obtained from at least one porous wood, or based on collagen fibers and hydroxyapatite, and a shell, based on hydroxyapatite (HA) or silicon carbide (SiC), obtained from at least one wood having a lower porosity than the at least one wood of the core. The porous wood has a total porosity of between 60% and 95%, preferably between 65% and 85%, and it is selected from amongst the choices of rattan, pine, abachi and balsa wood. The wood of the shell has a porosity of between 20% and 60%, preferably between 30% and 50%. The bone substitute is utilized for the substitution and regeneration of bone, preferably for bones subjected to mechanical loads, such as long bones of the leg and arm, preferably the tibia, metatarsus, femur, humerus or radius.

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