The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 03, 2016
Filed:
Jul. 29, 2011
James C. Paulson, Del Mar, CA (US);
Weihsu Claire Chen, Toronto, CA;
Norihito Kawasaki, San Diego, CA (US);
Corwin Nycholat, San Diego, CA (US);
James C. Paulson, Del Mar, CA (US);
Weihsu Claire Chen, Toronto, CA;
Norihito Kawasaki, San Diego, CA (US);
Corwin Nycholat, San Diego, CA (US);
The Scripps Research Institute, La Jolla, CA (US);
Abstract
The present invention provides liposome targeting compounds for targeting cells expressing sialic acid binding Ig-like lectin (Siglec). The liposome compounds typically comprise a binding moiety that is a glycan ligand of the Siglec on the target cell. The liposome compounds also incorporate or encapsulate a biological agent (e.g., an antigen or a therapeutic agent) that can be delivered to the target cell to modulate or kill the target cell. The invention also provides methods of using the liposome targeting compounds for targeted delivery of antigen and for modulating immune cells or immune responses.