The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 26, 2016
Filed:
Aug. 26, 2009
Applicant:
Nobuhiro Hoshino, Tokyo, JP;
Inventor:
Nobuhiro Hoshino, Tokyo, JP;
Assignee:
LSI MEDIENCE CORPORATION, Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/564 (2006.01); C07K 16/18 (2006.01); C07K 16/24 (2006.01); G01N 33/531 (2006.01); C07K 16/36 (2006.01); C07K 16/44 (2006.01);
U.S. Cl.
CPC ...
G01N 33/564 (2013.01); C07K 16/18 (2013.01); C07K 16/24 (2013.01); C07K 16/36 (2013.01); C07K 16/44 (2013.01); G01N 33/531 (2013.01); C07K 2317/21 (2013.01); C07K 2317/32 (2013.01); G01N 2800/222 (2013.01);
Abstract
Provided is a modified antibody which enables the quantitative measurement of the amount of a heparin/PF4 complex, an onset factor of heparin-induced trombocytopenia (HIT), without the influence of the presence of PF4, and which can be used as an HIT antibody standard specific for the heparin/PF4 complex. The modified antibody is prepared by linking a human IgG, or an antibody fragment derived from a human IgG, to a monoclonal antibody obtained by immunizing an animal (excluding a human) with the heparin/PF4 complex.