The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 26, 2016
Filed:
Oct. 07, 2013
Applicant:
General Electric Company, Schenectady, NY (US);
Inventors:
Anup Sood, Clifton Park, NY (US);
Arunkumar Natarajan, Niskayuna, NY (US);
Michael James Rishel, Saratoga Springs, NY (US);
Michael John Gerdes, Albany, NY (US);
Assignee:
General Electric Company, Niskayuna, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); G01N 33/68 (2006.01); G01N 33/53 (2006.01); G01N 33/533 (2006.01); G01N 33/542 (2006.01); G01N 33/543 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6825 (2013.01); G01N 33/53 (2013.01); G01N 33/533 (2013.01); G01N 33/542 (2013.01); G01N 33/6854 (2013.01); C12Q 2523/319 (2013.01);
Abstract
Disclosed are high throughput methods of probing multiple targets in a biological sample where the recurrent time-consuming antibody incubation steps and individual signal modification and activation steps are replaced by simultaneous hybridization of biomarkers and sequential detection by combining signal removal and activation into a single step. Also disclosed are images obtained by such methods.