The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 26, 2016

Filed:

Sep. 14, 2012
Applicants:

Subba Reddy Palli, Lansdale, PA (US);

Mohan Basavaraju Kumar, Harleysville, PA (US);

Dean Ervin Cress, Souderton, PA (US);

Ted Tsutomu Fujimoto, Churchville, PA (US);

Inventors:

Subba Reddy Palli, Lansdale, PA (US);

Mohan Basavaraju Kumar, Harleysville, PA (US);

Dean Ervin Cress, Souderton, PA (US);

Ted Tsutomu Fujimoto, Churchville, PA (US);

Assignee:

Intrexon Corporation, Blacksburg, VA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/06 (2006.01); C12N 15/63 (2006.01); C07K 14/705 (2006.01); C07K 14/72 (2006.01); C12P 21/02 (2006.01); C12P 21/04 (2006.01); C12N 5/07 (2010.01); C12N 5/071 (2010.01); C12N 5/00 (2006.01); C12N 15/00 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
C12N 15/635 (2013.01); C07K 14/70567 (2013.01); C07K 14/721 (2013.01); C12P 21/02 (2013.01);
Abstract

This invention relates to the field of biotechnology or genetic engineering. Specifically, this invention relates to the field of gene expression. More specifically, this invention relates to novel substitution mutant receptors and their use in a Group H nuclear receptor-based inducible gene expression system and methods of modulating the expression of a gene in a host cell for applications such as gene therapy, large scale production of proteins and antibodies, cell-based high throughput screening assays, functional genomics and regulation of traits in transgenic organisms.


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