The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 26, 2016
Filed:
Apr. 10, 2007
Shane Olwill, Belfast, GB;
Christopher Scott, Belfast, GB;
Julie Gormley, Belfast, GB;
Jaquin Thomas, Belfast, GB;
Roberta Burden, Belfast, GB;
Darragh Mcmeel, Belfast, GB;
James Johnston, Belfast, GB;
Shane Olwill, Belfast, GB;
Christopher Scott, Belfast, GB;
Julie Gormley, Belfast, GB;
Jaquin Thomas, Belfast, GB;
Roberta Burden, Belfast, GB;
Darragh McMeel, Belfast, GB;
James Johnston, Belfast, GB;
Fusion Antibodies Limited, , GB;
Abstract
The invention relates to a method of inhibiting chemotherapy induced upregulation of Cathepsin S on the surface of tumor cells, the method comprising the administration of a Cathepsin S inhibitor to said cells. Also provided is a therapy comprising an anti Cathepsin S antibody, in particular an anti-Cathepsin S antibody which does not inhibit the proteolytic effect of Cathepsin S but nevertheless inhibits angiogenesis and a combination treatment comprising a Cathepsin S inhibitor and a therapeutic agent.