The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 26, 2016
Filed:
Feb. 09, 2010
Chung-hsuan Chen, Taipei, TW;
Wei-chao Chang, Baihe Township, TW;
Michael Hsiao, Taipei, TW;
Ming-shyan Huang, Kaohsiung, TW;
Chih-jen Yang, Kaohsiung, TW;
Chung-Hsuan Chen, Taipei, TW;
Wei-Chao Chang, Baihe Township, TW;
Michael Hsiao, Taipei, TW;
Ming-Shyan Huang, Kaohsiung, TW;
Chih-Jen Yang, Kaohsiung, TW;
Academia Sinica, Taipei, TW;
Abstract
Methods for diagnosis of non-small cell lung cancers by detection of endogenous peptides in exhaled breath condensate (EBC) are provided. Diagnostic peptides derived from dermcidin (DC) are provided. A specific dermcidin-derived peptide E-R11, having the sequence ENAGEDPGLAR (SEQ ID NO:2), is provided. E-R11 peptide levels in EBC, as measured by mass spectrometry (MS), are highly diagnostic of non-small cell lung cancers. A method for inhibiting growth of lung cancer cells by inhibiting DCD expression by RNA interference also is provided.