The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 26, 2016

Filed:

Aug. 06, 2014
Applicant:

Claresa Levetan, Bryn Mawr, PA (US);

Inventor:

Claresa Levetan, Bryn Mawr, PA (US);

Assignee:

Perle Bioscience, Charleston, SC (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07K 7/08 (2006.01); A61K 38/10 (2006.01); A61K 38/13 (2006.01); A61K 47/48 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07K 7/08 (2013.01); A61K 38/10 (2013.01); A61K 38/13 (2013.01); A61K 45/06 (2013.01); A61K 47/48215 (2013.01);
Abstract

Embodiments of the present invention provide for novel therapies, pharmaceutical compositions and methods for insulin independence utilizing a new optimized hamster Reg3 gamma peptide, which is new to the art and has not previously been considered for development in the 30 year history since its discovery. Methods, pharmaceutical compositions and therapies novel to the prior art are utilized in this invention to render patients with recent onset and existing type 1 diabetes insulin independent by an optimized hamster Reg3 gamma peptide and an immune tolerance agent for type 1 patients to become insulin independent and used alone without an immune tolerance agent for type 2 diabetes. While not wishing to be bound by theory, optimized Reg3 gamma peptides increases beta cell generation by its demonstrated properties shown within of transforming ductal pancreatic cells into new islets.


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