The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 26, 2016

Filed:

Nov. 07, 2014
Applicants:

Incyte Corporation, Wilmington, DE (US);

Incyte Holdings Corporation, Wilmington, DE (US);

Inventors:

Ming Tao, Maple Glen, PA (US);

William Frietze, Kennett Square, PA (US);

David J. Meloni, Bear, DE (US);

Lingkai Weng, Malvern, PA (US);

Jiacheng Zhou, Newark, DE (US);

Yongchun Pan, Newark, DE (US);

Assignees:

Incyte Corporation, Wilmington, DE (US);

Incyte Holdings Corporation, Wilmington, DE (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/04 (2006.01); C07C 307/06 (2006.01); C07D 271/04 (2006.01); C07D 271/08 (2006.01);
U.S. Cl.
CPC ...
C07D 413/04 (2013.01); C07C 307/06 (2013.01); C07D 271/04 (2013.01); C07D 271/08 (2013.01);
Abstract

The present application is directed to processes and intermediates for making 4-({2-[(aminosulfonyl)amino]ethyl}amino)-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide, which is an inhibitor of indoleamine 2,3-dioxygenase, useful in the treatment of cancer and other disorders.


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