The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 26, 2016

Filed:

Feb. 24, 2015
Applicant:

University-industry Foundation, Yonsei University, Seoul, KR;

Inventors:

Seungjoo Haam, Seoul, KR;

Yong-min Huh, Seoul, KR;

Ilkoo Noh, Seoul, KR;

Jihye Choi, Incheon, KR;

Hyun-Ouk Kim, Seoul, KR;

Dayeon Yun, Seoul, KR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/14 (2006.01); A61K 9/51 (2006.01); A61K 47/48 (2006.01); A61K 31/7068 (2006.01); A61K 31/337 (2006.01);
U.S. Cl.
CPC ...
A61K 47/4823 (2013.01); A61K 31/337 (2013.01); A61K 31/7068 (2013.01); A61K 47/48315 (2013.01); A61K 47/48776 (2013.01); A61K 47/48238 (2013.01); Y10S 977/773 (2013.01); Y10S 977/906 (2013.01); Y10S 977/911 (2013.01);
Abstract

The present invention relates to a nanoparticle including a hydrophobic drug conjugated to a cationic polymer and a hydrophilic drug conjugated to an anionic polymer, a method of preparing the same and a pharmaceutical use thereof. The nanoparticle according to an embodiment of the present invention may deliver the hydrophilic drug and the hydrophobic drug at the same time, and may control an initial drug burst. Further, the nanoparticle according to an embodiment of the present invention is specific to a cancer cell environment, and thus selective diagnosis or treatment of cancer cells is possible.


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