The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 19, 2016

Filed:

Oct. 05, 2012
Applicant:

Brown University, Providence, RI (US);

Inventors:

Christoph Rose-Petruck, Barrington, RI (US);

Jack R. Wands, East Greenwich, RI (US);

Danielle Rand, Quincy, MA (US);

Zoltan Derdak, Riverside, RI (US);

Vivian Ortiz, Nashville, TN (US);

Assignees:

BROWN UNIVERSITY, Providence, RI (US);

RHODE ISLAND HOSPITAL, Providence, RI (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/574 (2006.01); G01N 33/569 (2006.01); A61K 49/04 (2006.01); B82Y 5/00 (2011.01);
U.S. Cl.
CPC ...
G01N 33/57438 (2013.01); A61K 49/0428 (2013.01); B82Y 5/00 (2013.01); G01N 33/56966 (2013.01); G01N 33/57484 (2013.01); G01N 2500/00 (2013.01);
Abstract

Methods, compositions, systems, devices and kits are provided herein for preparing and using a nanoparticle composition and spatial frequency heterodyne imaging for visualizing cells or tissues. In various embodiments, the nanoparticle composition includes at least one of: a nanoparticle, a polymer layer, and a binding agent, such that the polymer layer coats the nanoparticle and is for example a polyethylene glycol, a polyelectrolyte, an anionic polymer, or a cationic polymer, and such that the binding agent that specifically binds the cells or the tissue. Methods, compositions, systems, devices and kits are provided for identifying potential therapeutic agents in a model using the nanoparticle composition and spatial frequency heterodyne imaging.


Find Patent Forward Citations

Loading…