The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 19, 2016

Filed:

Jul. 18, 2014
Applicant:

Roche Diagnostics Operations, Inc., Indianapolis, IN (US);

Inventors:

Elke Faatz, Huglfing, DE;

Peter Schaarschmidt, Ulm, DE;

Urban Schmitt, Kochel, DE;

Christian Scholz, Penzberg, DE;

Assignee:

Roche Diagnostics Operations, Inc., Indianapolis, IN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/02 (2006.01); A61K 39/00 (2006.01); G01N 33/53 (2006.01); G01N 33/571 (2006.01); C07K 14/20 (2006.01);
U.S. Cl.
CPC ...
G01N 33/571 (2013.01); C07K 14/20 (2013.01); C07K 2319/00 (2013.01); G01N 2333/20 (2013.01); G01N 2469/20 (2013.01);
Abstract

The invention concerns soluble variants ofantigen 47 (TpN47 antigen) comprising at least domain B, or at least domains A and B, optionally domain D of the complete TpN47 protein molecule with the proviso that all antigens lack domain C (amino acid residues 224 to 351) of TpN47. The Tpn47 antigens can be fused to a chaperone. Moreover, the invention covers DNA encoding the antigens, a method of producing these antigens as well as the use of these antigens in an immunodiagnostic assay for the detection of antibodies againstin an isolated sample.


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