The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 19, 2016
Filed:
Jan. 14, 2011
Applicants:
Francine Behar-cohen, Paris, FR;
Elodie Touchard, La Milesse, FR;
Inventors:
Francine Behar-Cohen, Paris, FR;
Elodie Touchard, La Milesse, FR;
Assignee:
UNIVERSITE PARIS DESCARTES, Paris, FR;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); A61P 27/02 (2006.01); A61P 29/00 (2006.01); C07J 1/00 (2006.01); C12N 15/87 (2006.01); C07K 14/72 (2006.01);
U.S. Cl.
CPC ...
C12N 15/87 (2013.01); A61K 48/0083 (2013.01); C07K 14/721 (2013.01); C12N 2501/39 (2013.01); C12N 2510/00 (2013.01);
Abstract
A method for intracellular delivery of isolated naked nucleic acids into a biological tissue or organ, that includes (a) contacting the tissue or organ with an efficient amount of at least one active corticosteroid, and (b) contacting the tissue or organ treated in step b with an efficient amount of isolated naked nucleic acids, wherein step (a) is carried out for a period of time ranging from at least five minutes to at most two hours and being immediately followed by step (b).