The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 19, 2016

Filed:

Mar. 26, 2008
Applicants:

Hirofumi Takeuchi, Gifu, JP;

Yasuyuki Hira, Gifu, JP;

Koji Nakano, Gifu, JP;

Hidekazu Toyobuku, Tokushima, JP;

Inventors:

Hirofumi Takeuchi, Gifu, JP;

Yasuyuki Hira, Gifu, JP;

Koji Nakano, Gifu, JP;

Hidekazu Toyobuku, Tokushima, JP;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C07H 21/02 (2006.01); C12N 15/88 (2006.01); C12N 15/87 (2006.01); A61K 9/127 (2006.01); A61K 31/7088 (2006.01); A61K 31/713 (2006.01); C12N 15/11 (2006.01);
U.S. Cl.
CPC ...
C12N 15/87 (2013.01); A61K 9/127 (2013.01); A61K 31/7088 (2013.01); A61K 31/713 (2013.01); C12N 15/111 (2013.01); A61K 48/00 (2013.01); C12N 2310/14 (2013.01); C12N 2320/32 (2013.01);
Abstract

An object of the present invention is to provide a carrier composition for nucleic acid delivery, which can efficiently deliver a nucleic acid into cells when a nucleic acid such as siRNA is administered to animal-derived cells or animals, and also has low toxicity and high safety, and a composition for nucleic acid delivery containing the carrier composition and nucleic acid. A carrier for nucleic acid delivery is prepared by using (A) a diacylphosphatidylcholine, (B) at least one member selected from the group consisting of cholesterol and derivatives thereof, and (C) an aliphatic primary amine. Also, a composition for nucleic acid delivery is prepared by mixing the carrier for nucleic acid delivery with a nucleic acid.


Find Patent Forward Citations

Loading…