The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 19, 2016
Filed:
May. 07, 2012
Tomohiro Hamasaki, Fukuoka, JP;
Tadaaki Ohgi, Fukuoka, JP;
Tomohiro Hamasaki, Fukuoka, JP;
Tadaaki Ohgi, Fukuoka, JP;
BONAC Corporation, Kurume, JP;
Abstract
The present invention provides a process for preparing an isotope-containing phosphate compound easily. The process for preparing an isotope-containing phosphate compound according to the present invention includes the step of: oxidizing a trivalent phosphorus compound with an oxidizing agent containing an isotope to synthesize a pentavalent phosphate compound to which the isotope has been introduced. The present invention preferably is applied to the synthesis of nucleic acids such as DNA and RNA, for example. The isotope preferably is a stable isotope. The oxidizing agent preferably is HO, 3H-1,2-benzodithiol 3-one 1,1-dioxide havingS, or a diisopropylethylamine-borane complex havingB, for example.