The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 19, 2016
Filed:
Sep. 13, 2013
Tokyo Metropolitan Institute of Medical Science, Tokyo, JP;
Altif Laboratories Inc., Tokyo, JP;
Hitoshi Sakuraba, Chiba, JP;
Youichi Tajima, Tokyo, JP;
Ikuo Kawashima, Saitama, JP;
Seiichi Aikawa, Tokyo, JP;
Fumiko Aikawa, Tokyo, JP;
TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE, Tokyo, JP;
ALTIF LABORATORIES INC., Tokyo, JP;
Abstract
The present invention provides a pharmaceutical composition comprising a protein having α-galactosidase activity for treating Fabry disease, which causes no allergic side effect, which is highly stable in blood (plasma) and which can readily be taken up by a cell of an affected organ. The pharmaceutical composition for treating Fabry disease of the invention comprises, for example, a protein which acquires an α-galactosidase activity through alteration of the structure of the active site of wild-type human α-N-acetylgalactosaminidase.