The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 19, 2016
Filed:
Jul. 06, 2012
Adam Kelliher, Greater London, GB;
Angus Morrison, Greater London, GB;
Anil Oroskar, Lombard, IL (US);
Rakesh Vikraman Nair Rema, Lombard, IL (US);
Abhilesh Agarwal, Lombard, IL (US);
Adam Kelliher, Greater London, GB;
Angus Morrison, Greater London, GB;
Anil Oroskar, Lombard, IL (US);
Rakesh Vikraman Nair Rema, Lombard, IL (US);
Abhilesh Agarwal, Lombard, IL (US);
BASF Pharma Callanish Limited, Cheadle, Cheshire, GB;
Abstract
The present invention provides a chromatographic separation process for recovering a polyunsaturated fatty acid (PUFA) product from a feed mixture which is a fish oil or which is derived from fish oil, which process comprises the steps of: (i) purifying the feed mixture in a chromatographic separation step, to obtain a first intermediate product; and (ii) purifying the first intermediate product obtained in (i) in a simulated or actual moving bed chromatographic separation step, to obtain a second intermediate product; and (iii) purifying the second intermediate product obtained in (ii) in a simulated or actual moving bed chromatographic separation step, to obtain the PUFA product; wherein an aqueous organic solvent is used as eluent in each separation step; saturated and/or monounsaturated fatty acids present in the feed mixture are removed in the first separation step; the PUFA product is separated from different components of the feed mixture in steps (ii) and (iii); and the PUFA product obtained in the third separation step contains EPA or an EPA derivative in an amount greater than 90 wt %.