The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 19, 2016

Filed:

Mar. 13, 2012
Applicants:

Toru Miura, Saitama, JP;

Seiichi Sato, Tokyo, JP;

Hajime Yamada, Tokyo, JP;

Junya Tagashira, Tokyo, JP;

Toshiaki Watanabe, Tokyo, JP;

Ryohei Sekimoto, Osaka, JP;

Rie Ishida, Saitama, JP;

Hitomi Aoki, Tokyo, JP;

Tadaaki Ohgiya, Saitama, JP;

Inventors:

Toru Miura, Saitama, JP;

Seiichi Sato, Tokyo, JP;

Hajime Yamada, Tokyo, JP;

Junya Tagashira, Tokyo, JP;

Toshiaki Watanabe, Tokyo, JP;

Ryohei Sekimoto, Osaka, JP;

Rie Ishida, Saitama, JP;

Hitomi Aoki, Tokyo, JP;

Tadaaki Ohgiya, Saitama, JP;

Assignee:

KOWA COMPANY, LTD., Nagoya-shi, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/505 (2006.01); C07D 413/14 (2006.01); C07D 401/14 (2006.01); A61K 31/506 (2006.01);
U.S. Cl.
CPC ...
C07D 413/14 (2013.01); A61K 31/506 (2013.01); C07D 401/14 (2013.01);
Abstract

The present invention provides: a compound represented by general formula (I) below, that has both angiotensin II receptor antagonism and a PPARγ activation effect and that is useful as a preventative and/or therapeutic agent for high blood pressure, cardiac disease, arteriosclerosis, type-2 diabetes, and the like; and a drug composition containing the compound. General formula (I) (in the formula: ring A represents a pyridine ring; ring B represents a tetrazole ring or an oxadiazol-5(4H)-one ring; X represents C—Ror a nitrogen atom; Rrepresents an alkyl group; Rrepresents an alkyl group or a cycloalkyl group; and R, R, and Reach independently represents a hydrogen atom, a halogen atom, an alkyl group, an alkoxy group or similar.


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