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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9314467 B1

PDFFull Text
Date of Patent:
Apr. 19, 2016

Filed:

Feb. 25, 2015

Styrenyl derivative compounds for treating ophthalmic diseases and disorders

Applicant:

Acucela Inc., Seattle, WA (US);

Inventors:

Ian Leslie Scott, Monroe, WA (US);

Vladimir Aleksandrovich Kuska, Seattle, WA (US);

Anna Gall, Woodinville, WA (US);

Mark W. Orme, Seattle, WA (US);

Jennifer Gage, Kenmore, WA (US);

Thomas L. Little, Jr., Redmond, WA (US);

Qin Jiang, Latham, NY (US);

Lana Michele Rossiter, Clifton Park, NY (US);

Kevin F. McGee, Jr., Niskayuna, NY (US);

Ryo Kubota, Seattle, WA (US);

Assignee:

ACUCELA INC., Seattle, WA (US);

Attorney:

Wilson Sonsini Goodrich & Rosati

Primary Examiner:

Robert Havlin

Int. Cl.
CPC ...
C07C 211/27 (2006.01); A61K 31/137 (2006.01); A61K 31/5375 (2006.01); C07C 211/28 (2006.01); C07C 211/29 (2006.01); C07C 215/08 (2006.01); C07C 215/30 (2006.01); C07C 215/42 (2006.01); C07C 215/46 (2006.01); C07C 217/16 (2006.01); C07C 217/48 (2006.01); C07C 217/54 (2006.01); C07C 217/62 (2006.01); C07C 217/72 (2006.01); C07C 225/18 (2006.01); C07C 233/05 (2006.01); C07C 237/04 (2006.01); C07C 317/28 (2006.01); C07C 323/25 (2006.01); C07C 323/32 (2006.01); C07D 295/03 (2006.01); C07C 217/10 (2006.01); C07C 225/06 (2006.01); C07C 323/33 (2006.01); C07D 207/06 (2006.01); C07D 211/14 (2006.01); A61K 31/145 (2006.01); A61K 31/167 (2006.01); A61K 31/40 (2006.01); A61K 31/4453 (2006.01); A61K 31/495 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5375 (2013.01); A61K 31/137 (2013.01); A61K 31/145 (2013.01); A61K 31/167 (2013.01); A61K 31/40 (2013.01); A61K 31/4453 (2013.01); A61K 31/495 (2013.01); C07C 211/27 (2013.01); C07C 211/28 (2013.01); C07C 211/29 (2013.01); C07C 215/08 (2013.01); C07C 215/30 (2013.01); C07C 215/42 (2013.01); C07C 215/46 (2013.01); C07C 217/10 (2013.01); C07C 217/16 (2013.01); C07C 217/48 (2013.01); C07C 217/54 (2013.01); C07C 217/62 (2013.01); C07C 217/72 (2013.01); C07C 225/06 (2013.01); C07C 225/18 (2013.01); C07C 233/05 (2013.01); C07C 237/04 (2013.01); C07C 317/28 (2013.01); C07C 323/25 (2013.01); C07C 323/32 (2013.01); C07C 323/33 (2013.01); C07D 207/06 (2013.01); C07D 211/14 (2013.01); C07D 295/03 (2013.01); C07C 2102/14 (2013.01); C07C 2102/16 (2013.01);
Abstract

The present invention relates generally to compositions and methods for treating neurodegenerative diseases and disorders, particularly ophthalmic diseases and disorders. Provided herein are styrenyl derivative compounds, including but not limited to stilbene derivative compounds, and compositions comprising these compounds, that are useful for treating and preventing ophthalmic diseases and disorders, including age-related macular degeneration (AMD) and Stargardt's Disease.

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