The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 12, 2016

Filed:

Feb. 21, 2013
Applicant:

Metheresis Translational Research S.a., Lugano, CH;

Inventors:

Paolo Maria Comoglio, Turin, IT;

Paolo Carminati, Milan, IT;

Paolo Michieli, Rivalta di Torino, IT;

Cristina Basilico, Pavarolo, IT;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/09 (2006.01); C12N 15/113 (2010.01); C12N 15/115 (2010.01); G01N 33/68 (2006.01); C07K 14/71 (2006.01); G01N 33/566 (2006.01); C12N 5/10 (2006.01); A61K 38/17 (2006.01); A61K 48/00 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/68 (2013.01); C07K 14/71 (2013.01); G01N 33/566 (2013.01); A61K 38/00 (2013.01); A61K 38/179 (2013.01); A61K 48/00 (2013.01); G01N 2333/4753 (2013.01); G01N 2500/04 (2013.01);
Abstract

Use of a polynucleotide encoding or a polypeptide comprising at least the extra-cellular IPT-3 and IPT-4 domains of hepatocyte growth factor receptor for the screening and/or development of pharmacologically active agents useful in the treatment of cancer, preferably a cancer with dysregulation of hepatocyte growth factor receptor.


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