The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 12, 2016

Filed:

Oct. 27, 2010
Applicants:

Huafang Gao, Beijing, CN;

Guangxin Xiang, Beijing, CN;

Di Jiang, Beijing, CN;

Wanli Xing, Beijing, CN;

Jing Cheng, Beijing, CN;

Inventors:

Huafang Gao, Beijing, CN;

Guangxin Xiang, Beijing, CN;

Di Jiang, Beijing, CN;

Wanli Xing, Beijing, CN;

Jing Cheng, Beijing, CN;

Assignees:

CapitalBio Corporation, Beijing, CN;

Tsinghua University, Beijing, CN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/58 (2006.01); C12Q 1/68 (2006.01); C40B 30/04 (2006.01); G01N 33/543 (2006.01);
U.S. Cl.
CPC ...
G01N 33/582 (2013.01); C12Q 1/6816 (2013.01); C12Q 1/6837 (2013.01); C12Q 1/6883 (2013.01); C40B 30/04 (2013.01); G01N 33/54333 (2013.01); G01N 33/54386 (2013.01); C12Q 2600/156 (2013.01); C12Q 2600/158 (2013.01); C12Q 2600/16 (2013.01);
Abstract

A microarray-based assay is provided, which is used for analyzing molecular interactions, including polynucleotides, polypeptides, antibodies, small molecule compounds, peptides and carbohydrates. Such method comprises labeling a target molecule with a luminophore, coupling the target molecule to a particle, and binding to a probe molecule on microarray. In particular, multiplexed genetic analysis of nucleic acid fragments can be implemented. Specific genes, single nucleotide polymorphisms or gene mutations, such as deletions, insertions, and indels, can be identified. This technology, with high sensitivity, enables the detection and interpretation of molecular interactions in an efficient way.


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