The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 12, 2016
Filed:
Apr. 21, 2010
Yehoshua Shachar, Santa Monica, CA (US);
Winston Wu, Alhambra, CA (US);
Thomas Chen, La Canada, CA (US);
Leslie Farkas, Ojai, CA (US);
Brett Jordan, Los Angeles, CA (US);
Paladin Luboff, Santa Monica, CA (US);
Herwin Chan, Los Angeles, CA (US);
Kyle Zimmerman, Los Angeles, CA (US);
Yehoshua Shachar, Santa Monica, CA (US);
Winston Wu, Alhambra, CA (US);
Thomas Chen, La Canada, CA (US);
Leslie Farkas, Ojai, CA (US);
Brett Jordan, Los Angeles, CA (US);
Paladin Luboff, Santa Monica, CA (US);
Herwin Chan, Los Angeles, CA (US);
Kyle Zimmerman, Los Angeles, CA (US);
Sensor-Kinesis Corporation, Los Angeles, CA (US);
Abstract
An aptamer-based solid-state electrochemical biosensor for label-free detection ofserovars utilizing immobilized aptamers. The device is realized by forming a matrix array of parallel capacitors, thus allowing the realization of low-cost, portable, fully integrated devices. Protein-aptamer binding modulates the threshold voltage of a circuit, changing the impedance (capacitance) of the circuit. This circuit is further characterized by an electrode coded with a p-Si substrate, enhancing the affinity between theouter membrane proteins (OMPs) and the aptamer. An aptamer embedded detection plate is configured within a testing lid device that fits a standard, commercially available polymer specimen jar. A sample is mixed with broth for incubation and cultivation of any presentbacteria to obtain acceptable concentration of the pathogen for testing. The information obtained can then be transmitted by wireless network.