The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 12, 2016
Filed:
Aug. 28, 2008
Applicants:
Scott E. Kern, Hunt Valley, MD (US);
Eike Gallmeier, Germering, DE;
Tomas Hucl, Baltimore, MD (US);
Inventors:
Assignee:
The Johns Hopkins University, Baltimore, MD (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); C12N 15/10 (2006.01); C40B 30/06 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1082 (2013.01); C40B 30/06 (2013.01);
Abstract
Provided herein are compositions and methods for assaying the deleteriousness of putative loss-of-function mutations, especially in genes known to be or suspected of being tumor-suppressor genes. The invention includes syngeneic variance libraries and methods of construction and use of syngeneic variance libraries.