The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 12, 2016
Filed:
Jun. 11, 2014
Hoffmann-la Roche Inc., Little Falls, NJ (US);
Georg Fertig, Penzberg, DE;
Jens Fischer, Weilheim in Oberbayern, DE;
Guy Georges, Habach, DE;
Klaus Kaluza, Weilheim, DE;
Valeria Lifke, Penzberg, DE;
Joerg Moelleken, Munich, DE;
Sonja Offner, Penzberg, DE;
Achal Pashine, Mahwah, NJ (US);
Stefan Seeber, Penzberg, DE;
HOFFMANN-LA ROCHE INC., Little Falls, NJ (US);
Abstract
An antibody binding to IL33R characterized in that the heavy chain variable domain comprises a CDR3 region of SEQ ID NO:1, a CDR2 region of SEQ ID NO:2 and a CDR1 region of SEQ ID NO:3 and in that the light chain variable domain comprises a CDR3 region of SEQ ID NO:4, a CDR2 region of SEQ ID NO:5 and a CDR1 region of SEQ ID NO:6 or a a chimeric, humanized or T cell epitope depleted antibody variant thereof has advantageous properties for the treatment of inflammatory diseases.